Drontal Plus XL

Why pets deserve Drontal

Regularly Parasitic worms infect most dogs at some time in their lives. They could damage your pet's well-being. Some worms can infect people, & their larval periods can cause numerous health problems, with children being most at risk. That’s why every responsible pet owner should make regular worming part of the canine healthcare routine

For the control of the following gastrointestinal roundworms & tapeworms of canines & pups. 

  • Ascarids Toxocara canis - Toxascaris leonina [ mature & late immature types ].
  • Tapeworms Echinococcus species - Taenia species, Dipylidium caninum [ mature & immature types ].
  • Hookworms Uncinaria stenocephala - Ancylostoma caninum [ mature ].
  • Whipworms Trichuris vulpis [ mature ].

Available in strips of 2, 8 or 48 tablets

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Effective Worm Control
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How frequently should dogs be treated for worms ?

Prevent dogs getting worms

 

 

 

 

It’s hard to prevent worm disease, therefore it is advisable for one to treat your dogs often for worms. Worming at least every three months will help keep your dogs healthy and, significantly, reduce the amount of worm eggs shed into the surroundings. Energetic dogs are particularly susceptible to tapeworm infections due to the creatures they they come into contact, like rodents which act as intermediate hosts for several tapeworm species. Monthly worming is strongly urged for the dog's healthcare routine.

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Drontal Plus XL

Drontal Plus XL




Drontal Plus Flavour Tablets are a light brown to brown, circular pill, mix scored on a single Aspect for oral administration to pets, comprising 50 mg praziquantel, 144 mg pyrantel embonate and 150 mg febantel as effective ingredients and 116.5 mg Synthetic Meat quality drawn.

Drontal Plus XL Flavor Pill is just a light brown to brown square-formed divisible pill scored on both Attributes comprising 175 mg praziquantel, 504 mg pyrantel embonate and 525 mg febantel as active ingredients and 408.0 mg Synthetic meat flavor drawn. Uses for That handle of the next intestinal roundworms and tapeworms of pets and puppies

Reviews
"A very fast delivery , my dogs love em plus it's keeping him worm free and very easy to use .Great price much much more economical than purchasing at my vets for the same product will use supplier again. They work brilliantly !"
Anne
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Dosage Guide

Dosage Guide- Drontal Plus XL Flavour Tablets ***

  • 17.5 kg body weight = tablet
  • 17.5 - 35 kg body weight = 1 tablet
  • 35 - 52.5 kg body weight = 1 pills
  • 52.5 - 70 kg body weight = 2 tablets

Drontal Plus Flavour Tablets should be used to achieve accurate dosing in dogs weighing less than 17.5 kg. The dose is equivalent to 1 tablet per 10 kg. The pills can be given directly to the dog or disguised in food. No starvation is required before or after treatment.

For routine treatment one dose is recommended. Pups should be treated at 2 weeks old and every 2 weeks until 12 weeks old. Then they should be treated at 3 month periods. It is best to treat the bitch at exactly the same time as the pups. Not for use in dogs weighing less than 3 kg. For the control of Toxocara, nursing bitches should be dosed 2 weeks after giving birth and every two weeks until weaning.

For routine control mature dogs should be treated every 3 months. For routine treatment a single dose is advocated. In the event of significant roundworm Illness a repeat dose should be given after 14 days. Use During Pregnancy and Lactation: Consult a veterinary surgeon before treating pregnant animals for roundworms. The product may be used during lactation. Don't exceed recommended dose when treating pregnant bitches. . *** It is crucial to read all of the instructions before administering treatment to your own canine

Worming tablets
"Having two German Shepherds their noses are every where so they got worms and we have consistently used Drontal as it gets eaten up immediately and no worms since ! They are now in the greatest of health and considerably more joyful with us . Why pay veterinarians costs for fundamental pills when you are able to get these cheaper without a prescription? Found this website and they do a fantastic cost and arrived so fast. Excellent and now I 've joyful pets and that makes me happy to"
Colin
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I wouldn't hesitate to purchase again
"The pills were provided by my veterinarian's the last time I purchased them but they were a lot more in price.These are nicely priced arrived promptly and do the job very well.It says on the box tend not to halve but I did as my veterinarian's said as this was fine last time .It's useful to have a precise mass of how much your dog weighs so it is possible to give your dog the right dosage. This is an excellent product which I wouldn't hesitate to purchase again"
Sarah.F
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Hookworms Uncinaria stenocephala, Ancylostoma caninum

Hookworms

Hookworms Uncinaria stenocephala, Ancylostoma caninum

  • Hookworms are one of the most common parasitic nematodes which infect mammals including cats, dogs, humans, and wild canids. They're widespread in tropical and temperate areas of the world. Now, more than 100 species belonging to 18 genera of hookworms are discovered, parasitizing the intestinal tract of herbivore and carnivore animal hosts.

Ascarids Toxocara canis Toxascaris leonina

Ascarids

Ascarids Toxocara canis Toxascaris leonina

  • Toxocara canis & Toxocara cati are the two leading ascarids worldwide infecting cats & dogs . Both species have a fascinating & complicated biological cycle, which relies on distinct pathways of transmission & larval migrations, depending upon largely the supply of disease & animal age.



Anywhere they go they can pick up worm eggs from their environment as they rummage about .The eggs are consumed and enter the bowel where larvae hatch in the worm egg .Depending on the creature's age and the strength of its immune system the foyer penetrate the intestinal wall and embark on their migration through the body .They enter the blood vessels and are carried in the bloodstream to various organs .These organs are damaged by the migratory movements of the worm larvae in young creatures the larvae frequently went to the liver after which to the lungs by the blood streams .From here they reach the path here are cuffed up swallowed and travel through the esophagus to the intestine where they settle and develop into mature egg laying adults. Adult worms can create up to 200,000 eggs daily the worm eggs which are undetectable to the naked eye are excreted in the animal species. They are able to survive for several years in the earth and act as a source of infection for other animals. Some of the worm larvae do not return to the intestine they become encapsulated largely in intrastate and the muscles of dormancy. These arrested larvae in the muscles are the reasons why worms are carried during the final trimester of pregnancy to her pups from your bitch. The dormant anteroom are reactivated by hormones they traveled to the uterus by the bloodstream and infect the unborn pups. The mammary gland is reached by other foyer by the bloodstream newborn pups and kittens can subsequently be infected through their mother's milk
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Whipworms Trichuris vulpis

Whipworms

Whipworms Trichuris vulpis


  • Parasitic nematodes belonging to the family Trichuridae infest human beings as well & domestic animals, & wild. The so-called?canine whipworm is it & the known changes the large bowel of dogs & wild canids. The life cycle of T. vulpis , which is direct & based on a soil-transmitted oral course of infestation via embryonated eggs, is well understood, albeit some biological aspects of this nematode (e.g., blood-sucking & zoonotic skills) have yet to be elucidated..

Tapeworms a class of parasitic flatworms

Tapeworms Echinococcus species, Taenia species, Dipylidium caninum

Tapeworms Echinococcus species, Taenia species, Dipylidium caninum

  • The dog tapeworm E. granulosus is one of a group of medically important parasitic helminths of the family Taeniidae (Platyhelminthes; Cestoda; Cyclophyllidea) that infect at least 50 million people worldwide . Its life cycle affects two mammals, including an intermediate host, usually a domestic or wild ungulate (people are accidental intermediate hosts) & a canine-definitive host, like the domestic dog. The larval (metacestode) phase causes hydatidosis (cystic hydatid disease; cystic echinococcosis), a long-term cyst-forming disorder in the intermediate (person) host. Now, up to 3 million individuals are infected with E. granulosus , &, in some places, 10% of the inhabitants has detectable hydatid cysts by abdominal ultrasound & chest X-ray
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Further information

Pharmacotherapeutic group - Anthelmintics, tetrahydropyrimidine. ATC Vet Codes: QP52AF30, QP52AC55. **

The product includes three active substances active against roundworms & tapeworms

  • Febantel, a probenzimidazole,
  • Pyrantel embonate (pamoate) a tetrahydropyrimidine derivative,
  • Praziquantel, a partly hydrogenated pyrazinoisoquinoline derivative.

Praziquantel is a partially hydrogenated pyrazinoisoquinoline derivative used extensively as an anthelmintic for both human & veterinary use. In this fixed mix pyrantel & febantel act against all important nematodes (ascarids, hookworms, & whipworms) in dogs. In particular the action spectrum covers Toxocara canis, Toxascaris leonina, Uncinaria stenocephala, Ancylostoma caninum & Trichuris vulpis.

This combination shows synergistic activity in the case of hookworms & febantel is successful against T.vulpis. The spectrum of activity of praziquantel covers all important cestode species in dogs, in particular Taenia spp Dipylidium caninum, Echinococcus granulosus & Echinococcus multilocularis. Praziquantel acts against all adult & immature kinds of these parasites. Pyrantel acts as a cholinergic agonist. Its mode of action will be to stimulate nicotinic cholinergic receptors of the parasite, induce spastic paralysis of the nema todes & therefore allow removal from your gastrointestinal system by peristalsis.

Within the mammalian system febantel under goes ring closure forming fenbendazole & oxfendazole. It's these chemical things which apply the anthelmintic effect by inhibition of tubulin polymerization. Formation of microtubules is thus prevented, resulting in dislocation of arrangements critical to the ordinary function of the helminth. Glucose uptake specifically is changed, leading to a depletion in cell ATP. The parasite dies upon exhaustion of its energy reserves, which occurs 2-3 days later. Praziquantel is quite rapidly absorbed through the parasite’s surface & spread throughout the parasite. Both in vitro & in vivo studies have shown that praziquantel causes serious damage to the parasite integument, leading to the contraction & paralysis of the parasites. There's an almost instantaneous tetanic contraction of the parasite musculature & a fast vacuolization of the syncytial tegument. This rapid contraction has been explained by changes in divalent cation fluxes, particularly calcium.

Since it comprises praziquantel, the product is effective against Echinococcus multilocularis, which does not happen in the UK but is becoming more common in some European nations. As a precautionary measure to prevent establishment of E. multilocularis in the UK & Irel, it's recommended that all dogs entering the nation travelling either under the PETS scheme (UK only) or going into quarantine (UK & Irel) be treated with praziquantel. Fleas serve as intermediate hosts for one common kind of tapeworm - Dipylidium caninum. Tapeworm infection is sure to re occur unless control of intermediate hosts like fleas, mice etc. is undertaken.

** It is crucial to read all of the instructions before administering treatment to your own canine

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